Differences in incidence of delirium when using remimazolam or dexmedetomidine in elderly patients undergoing orthopedic surgery under spinal anesthesia

Differences in postoperative delirium incidence when dexmedetomidine or remimazolam was used as intra-operative sedation in patients aged 70 years or older undergoing orthopedic lower extremity surgery under spinal anesthesia

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0008346

Enrollment

Registered

2023-04-11

Start date

2022-11-22

Completion date

Unknown

Last updated

2023-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : In the experimental group, remimazolam is used for sedation during spinal anesthesia, and in the control group, dexmedetomidine is used for sedation during spinal anesthesia. Experimental group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: - Adults aged 70 years or older who are receiving orthopedic surgery of the lower extremities under spinal anesthesia - ASA classification 1-3

Exclusion criteria

Exclusion criteria: - Patients diagnosed with delirium, dementia, cognitive disorders - Anesthesia plan changed from spinal anesthesia to general anesthesia, for any reasons - Inappropriate to give sedatives due to patient's general condition - Patient's refusal to participate

Design outcomes

Primary

Measure	Time frame
Incidence of delirium up to 5 days after surgery	—

Secondary

Measure	Time frame
Onset time to sedation after drug injection;Arousal time after drug discontinuation;Intra-operative hypotension, bradycardia, apnea, desaturation;Hypotension, bradycardia, prolonged sedation at the post-anesthesia care unit	—

Countries

Korea, Republic of

Contacts

Public ContactHeeyeon Sung

Dankook Univeristy Hospital

pl2mouth@naver.com+82-41-550-6814

Outcome results