None listed
Conditions
Interventions
Dietary Supplement, Others : 1. Exercise intervention in the experimental group will be exercised for a total of 24 weeks, and the subject will visit the department of rehabilitation medicine at Chung
protein: 20 g [50% casein + 40% whey + 10% soy, total leucine: 3000 mg], vitamin D: 800 IU [20 µg], calcium: 300 mg, fat: 1.1 g, carbohydrate: 2.5 g
Maeil Dairies Co., Ltd., Seoul, South Korea)
Sponsors
Chungnam National University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Post-menopausal female aged between 65 years and 90 years 2. Diagnosed with sarcopenia 3. Diagnosed with osteopenia or osteoporosis
Exclusion criteria
Exclusion criteria: 1. secondary osteoporosis 2. regularly taking medications that can affect the bone or muscle more than a month before the study (e.g., anticonvulsants, steroids) 3. a diagnosis of diabetes mellitus, thyroid disease, parathyroid disease, or Paget’s disease of bone 4. active malignancy requiring treatment 5. having implants, hardware, devices, or foreign material in the measurement area 6. chronic kidney disease more severe than stage 3 (GFR<60 ml/min) 7. alcohol addiction 8. a history of previous fragile fractures (radius, hip, or spine) 9. inability to understand or to participate in the study protocol 10. refusal to participate.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The patient's appendicular muscle mass, skeletal muscle index, and bone mineral density (measurement site - spine, femur neck) measured through DEXA scan | — |
Secondary
| Measure | Time frame |
|---|---|
| Appendicular muscle mass, whole-body phase angle, lean body mass, total fat mass (%) and skeletal muscle index measured by bioelectrical impedance analysis, patient's quality of life and psychological state, patient's functional evaluation, muscle quality, and CTX | — |
Countries
Korea, Republic of
Contacts
Public ContactKyung-il Kim
Chungnam National University
Outcome results
None listed