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The analgesic effect of nefopam on postoperative pain and quality of recovery in patients undergoing laparoscopic cholecystectomy: A randomized, single-blind, prospective study

The analgesic effect of nefopam on postoperative pain and quality of recovery in patients undergoing laparoscopic cholecystectomy: A randomized, single-blind, prospective study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0008281
Enrollment
40
Registered
2023-03-08
Start date
2023-03-13
Completion date
Unknown
Last updated
2023-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : During surgery, 40 mg of nefopam is mixed with 100 ml of normal saline and administered intravenously for intervention group.

Sponsors

The Catholic University of Korea, Eunpyeong St. Mary's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) American Society of Anesthesiologists (ASA) physical status I or II 2) adults between 19 and 75 years of age.

Exclusion criteria

Exclusion criteria: 1) Patients who disagree with the study 2) Patients who have difficulty understanding and agreeing with the explanation of the study due to cognitive impairment. 3) Pregnant women and lactating women 4) American Society of Anesthesiologists (ASA) physical status 3 or higher 5) Age under 19 or over 75 6) a patient with a history of convulsions or convulsions 7) Patients receiving MAO inhibitors and anti-cholinergic drugs 8) Patients with urethral and prostate disorders 9) Patients with closed-angle glaucoma (increased intraocular pressure)

Design outcomes

Primary

MeasureTime frame
RUQ pain(Visceral pain)

Secondary

MeasureTime frame
Umbilicus pain(Somatic pain), Shoulder pain(Referred pain);Patients' satisfaction(QoR 15 questionnaire)

Countries

Korea, Republic of

Contacts

Public ContactSoyeon Lee

The Catholic University of Korea, Eunpyeong St. Mary's Hospital

soyeon0719@songeui.ac.kr+82-2-2030-3862

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026