Effectiveness of multi-channel direct current stimulation applied to the scalp on weaning from the ventilator in critically ill patients with acute respiratory failure

Effectiveness of high-definition transcranial direct current stimulation for weaning from mechanical ventilation in critically ill patients with acute respiratory failure. – single center, double blind, randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0008232

Enrollment

Registered

2023-02-27

Start date

2023-03-27

Completion date

Unknown

Last updated

2023-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : A. Control group (sham stimulation) - Sham stimulation by HD-tDCS on Lt. diaphragmatic primary motor cortex 30 mins, 10 consecutive weekdays with two sessions per day for 2 weeks -

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ? Patients aged 19 years or older admitted to an intensive care unit ? If a specialist diagnoses the acute respiratory failure ? Patients who received invasive mechanical ventilation for more than 24 hours

Exclusion criteria

Exclusion criteria: ? Pregnant women ? A condition in which respiratory muscle training is impossible due to neuropathy or congenital muscle disease ? Brain death ? Patients with severe traumatic brain injury ? Patients with brain lesions (infarction and hemorrhage in the brain stem) that can affect breathing capacity ? Patients with a history of epilepsy/seizures ? Patients with intracranial metal implants (coils, clips, etc.) ? Patients with implanted cardiac pacemakers ? Patients who did not consent to this study ? If a neurologist or psychiatrist has diagnosed cognitive dysfunction ? If the diaphragm is dysfunctional due to diaphragmatic trauma or hernia ? Patients with chest trauma, multiple trauma or general burns, open thorax or open heart surgery ? Terminally ill patients with severe cachexia or less than 12 months of life expectancy ? Patients with chronic respiratory failure using a home ventilator ? Patients using an extracorporeal membrane oxygenation (ECMO)

Design outcomes

Primary

Measure	Time frame
Mechanical ventilation application period	—

Secondary

Measure	Time frame
Richmond Agitation-sedation Scale;Medical Research Council sum score;Grip strength;Functional Status Score for the Intensive Care Unit;The Confusion Assessment Method for the Intensive Care Unit;Korean Hamilton Depression Rating Scale;Hospital Anxiety and Depression Scale;Impact of Events Scale-Revised ;Geriatric Depression Scale-short form ;Depression Anxiety Stress Scale ;Peak expiratory flow;EuroQol-5D-5L; Maximal inspiratory pressure;Maximal expiratory pressure;6-minute walk test	—

Measure

Time frame

Richmond Agitation-sedation Scale;Medical Research Council sum score;Grip strength;Functional Status Score for the Intensive Care Unit;The Confusion Assessment Method for the Intensive Care Unit;Korean Hamilton Depression Rating Scale;Hospital Anxiety and Depression Scale;Impact of Events Scale-Revised ;Geriatric Depression Scale-short form ;Depression Anxiety Stress Scale ;Peak expiratory flow;EuroQol-5D-5L; Maximal inspiratory pressure;Maximal expiratory pressure;6-minute walk test

—

Countries

Korea, Republic of

Contacts

Public ContactYeongwook Kim

Chungnam National University Sejong Hospital

kyu0922@hanmail.net+82-44-995-4760

Outcome results