Comparison of patient-controlled analgesia with background opioid versus non-opioid infusion for postoperative pain in patients undergoing total knee arthroplasty

Comparison of patient-controlled analgesia with background opioid versus non-opioid infusion for postoperative pain in patients undergoing total knee arthroplasty: a randomized, non-inferiority study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0008154

Enrollment

Registered

2023-02-03

Start date

2023-01-26

Completion date

Unknown

Last updated

2024-07-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Patients who undergoing total knee arthroplasty under spinal analgesia will be recruited and randomly assigned to the following two groups according to the regimen of PCA: (A) opioid group who

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: We will enrolled patients aged 60-78 years with ASA physical status I–II, and undergoing elective total knee arthroplasty under spinal anesthesia.

Exclusion criteria

Exclusion criteria: We will exclude patients with risk of complications associated with fentanyl, ketorolac, and nefopam. Those who are contraindicated to undergo spinal anesthesia will be also excluded.

Design outcomes

Primary

Measure	Time frame
The primary outcome is the pain score evaluated by visual analogue scale 24 hours after the surgery.	—

Secondary

Measure	Time frame
the total amount of drugs infused for postoperative pain control	—

Countries

Korea, Republic of

Contacts

Public ContactSe-Hee Min

Chung-Ang University Gwangmyeong Hospital

seiheemin@gmail.com+82-2-2222-1534

Outcome results