None listed
Conditions
Interventions
None listed
Sponsors
Ajou University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: A. Patients with a diagnosis of asthma in electronic health records from 1994 to February 2022 B. Patients 18 years of age or older C. Patients taking a medium-high dose inhaled corticosteroid-long-acting beta-agonist (ICS-LABA) that corresponds to step 4/5 of the GINA guidelines D. Patients who have experienced 2 or more asthma exacerbations
Exclusion criteria
Exclusion criteria: A. Patients under the age of 18 B. Past history of significant diseases that may affect the clinical outcome of asthma (autoimmune disease, malignant tumor disease, chronic infectious disease) C. Patients with chronic obstructive pulmonary disease (COPD) D. Patients who were diagnosed with asthma but not received any asthma medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Anti-IL-4/13 respond | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in FEV1%;Changes in eosinophil/neutrophil counts in blood and sputum;Asthma medication use;Annual rate of asthma exacerbation;Immunological biomarker (total IgE, specific IgE);Inflammatory markers (ECP, EDN, MPO) | — |
Countries
Korea, Republic of
Contacts
Public ContactYoungsoo Lee
Ajou University Hospital
Outcome results
None listed