Comparison for characteristics of sedation, using dexmedetomidine and remimazolam, in spinal anesthesia

Comparison of remimazolam and dexmedetomidine as a sedative during spinal anesthesia

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0008127

Enrollment

Registered

2023-01-17

Start date

2023-02-01

Completion date

Unknown

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : 1. Prepare 1mg/mL of Remimazolam total volume 50mL by mixing a Remimazolam 1 vial (50mg) to normal saline 50mL. Dilute 4mcg/mL of dexmedetomidine (50mL premix) in normal saline and prepare 1mcg

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients undergoing orthopedic surgery under spinal anesthesia at Konkuk University Medical Center

Exclusion criteria

Exclusion criteria: 1) any contra-indication of spinal anesthesia, 2) any contra-indication for the use of dexmedetomidine or remimazolam, 3) urgent or emergent case, 4) history of drug abuse, 5) QT prolongation on preoperative electrocardiography and 6) other concurrent surgery.

Design outcomes

Primary

Measure	Time frame
Emergence time after sedation	—

Secondary

Measure	Time frame
Sedation time after administration of drug;Sedation scale;Hemodynamic stability (blood pressure, heart rate, respiratory rate)	—

Countries

Korea, Republic of

Contacts

Public ContactSeung-wan Hong

Konkuk University Medical Center

20150077@kuh.ac.kr+82-2-2030-5448

Outcome results