None listed
Conditions
Interventions
Medical Device : A transcranial DC stimulator was provided to the subjects and administered once in the hospital, and then administered at home for 13 days every day, so that tDCS treatment could be a
Sponsors
National Health Insurance Service Ilsan Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Adults over 19 years of age and under 65 years of age with a history of confirmed coronavirus 2) A person who subjectively complains of cognitive decline, such as memory impairment and decreased concentration, after being confirmed with COVID-19 3) A person who is diagnosed as appropriate for a depressive disorder through an evaluation according to a clinical interview with a psychiatrist (PHQ-9 scale of 5 or more) 4) A person who can read and understand the research subject's explanation and consent form, and speaks Korean 5) A person who voluntarily decides to participate in this clinical study and who agrees in writing to the automatic medical certificate subject to the study and can participate in the entire clinical study period
Exclusion criteria
Exclusion criteria: 1) A person whose medical examination has found other neurological abnormalities that may cause memory impairment 2) A person with a history of uniaxial psychiatric disorders, including intellectual disabilities, schizophrenia, alcoholism, and bipolar disorder 3) A person who has been evaluated as two or more points in question 3 of HAM-D, or who has attempted suicide within the last six months 4) When it is deemed that there is a problem with attaching electrodes to the brain waves and direct current stimulation due to abnormalities in the scalp, inflammatory reactions, or other dermatological problems 5) Those who are treated with medical diagnosis that may interfere with participation in this experiment, including stroke, spasmodic disease, multiple sclerosis, cerebral palsy, huntington disease, encephalitis, meningitis, liver disease, kidney disease, etc 6) A person who has undergone surgery on cerebral blood vessels, such as brain surgery or carotid artery surgery 7) A person who is hard to understand a conversation because of hearing impairment even with hearing aids 8) A person who can't read normal letters even with glasses on because of poor eyesight 9) In addition to the above, a person who has clinically significant findings that are medically deemed inappropriate for this study by the research director or person in charge 10) A person who has experienced a decrease in cognitive ability before being confirmed to have a coronavirus infection 11) A person who experiences depression illustrations or has a history of taking antidepressants during the period from 2 months before the confirmation of the coronavirus infection to the time of the confirmation of the coronavirus infection 12) A person who has a history of taking antidepressants within the last one month
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| 1) Changes in DOT probe task results before and after tDCS application, 2) Average change in Multifactional Memory Questionnair (MMQ) results before and after tDCS application, 3) Electroencephalography (EEG) changes in activity by part of the brain | — |
Primary
| Measure | Time frame |
|---|---|
| 1) 1) Interference selection in the comprehensive attention test before and after tDCS application, the change in the results of the suppression continuity test / 2) The change in the Hamilton Depression scale (HAM-D) results before and after tDCS application | — |
Countries
Korea, Republic of
Contacts
Public ContactJung Eun Kim
National Health Insurance Service Ilsan Hospital
Outcome results
None listed