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A human study to evaluate the effectiveness and safety of propolis extract on skin condition improvement in children with atopic dermatitis: a randomized, double-blind, parallel, placebo-controlled study

A human study to evaluate the effectiveness and safety of propolis extract on skin condition improvement in children with atopic dermatitis: a randomized, double-blind, parallel, placebo-controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0008041
Enrollment
84
Registered
2022-12-29
Start date
2023-06-23
Completion date
Unknown
Last updated
2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Dietary Supplement : On the screening visit, subject who voluntarily signs on the written informed consent is reviewed according to inclusion-exclusion criteria. After 2 weeks of run-in period, subjec

Sponsors

Seoul National University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Subject who voluntarily agrees to participate and subjects and their parents (or legal representatives) sign in informed consent form 2) The ages of between 4 and 65 with intermittent or persistent symptoms of atopic dermatitis for more than 6 months

Exclusion criteria

Exclusion criteria: 1) Subjects who have systemic diseases such as skin diseases except for atopic dermatitis, immunodeficiency, autoimmune diseases, cancer, etc. 2) Use of systemic antibiotics, corticosteroids, or immunosuppressants related to atopic dermatitis within 1 month of the first visit 3) Use of medication related atopic dermatitis such as antihistamines, herbal medicines, or health functional foods within 1 month of the first visit 4) Presence of received phototherapy within 1 month of the first visit 5) History of hypersensitivity including ingredients (propolis, honey) or pollen in the placebo/test material, or severe food allergic reactions 6) Subjects who plan to participate in another clinical trial during current participation 7) Participation in another clinical trial within 1 month of the first visit 8) Subjects who, in the investigator's judgment, have a condition that would not allow to participate in the study

Design outcomes

Primary

MeasureTime frame
Markers of atopic dermatitis

Secondary

MeasureTime frame
Adverse event, vital signs

Countries

Korea, Republic of

Contacts

Public ContactKyeong Jin Kim

Seoul National University of Science and Technology

jinnykim@seoultech.ac.kr+82-2-974-6740

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026