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Comparison of recovery profiles of remimazolam-remifentanil and propofol-remifentanil in elderly patients undergoing laparoscopic abdominal surgeries

Comparison of recovery profiles of remimazolam-remifentanil and propofol-remifentanil in elderly patients undergoing laparoscopic abdominal surgeries

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CRIS
Registry ID
KCT0008005
Enrollment
120
Registered
2022-12-13
Start date
2022-12-05
Completion date
Unknown
Last updated
2023-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Randomly assigned propofol or remimazolam as an intravenous anesthetic used for general anesthesia Both drugs are used at doses within the scope of approval by the Ministry of Food and Drug Sa

Sponsors

Dong-A University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: ? American Society of Anesthesiology Physical Grade I, II, III ? Patients aged 60 years or older who agreed to participate in the study ? Patients who will undergo laparoscopic abdominal surgery for more than 3 hours for stomach or colorectal cancer ? Patients undergoing regular surgery at Dong-A University Medical Center

Exclusion criteria

Exclusion criteria: ? Patients with obvious respiratory and cardiovascular dysfunction ? Patients with abnormal blood test values ? Severe neuropsychiatric patients ? Patients who have used benzodiazepines and opioids within 1 month ? Patients with drug hypersensitivity or contraindications ? Patients with uncontrolled diabetes ? Pregnant or breastfeeding women ? Patients who plan to give birth within 3 months ? Patients with BMI > 35 or more ? Patients who are expected to have a difficult airway

Design outcomes

Primary

MeasureTime frame
Comparison of QoR-15 (quality of recovery-15) scores on the third day after surgery

Secondary

MeasureTime frame
Intraoperative blood pressure, pulse rate, oxygen saturation, BIS (Bispectral index), drug use, intraoperative wakefulness, eye opening time, extubation time, anesthesia recovery time, occurrence of side effects and complications in the recovery room, awakening delirium

Countries

Korea, Republic of

Contacts

Public ContactSeok hyun Ma

Dong-A University Hospital

msh9531@naver.com+82-51-240-5390

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026