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A Study on the Human Application for the Prevention of Implant Peripheral Inflammation by Intake of probiotics Weissella cibaria CMU

A Study on the Human Application for the Prevention of Implant Peripheral Inflammation by Intake of probiotics Weissella cibaria CMU

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0007978
Enrollment
44
Registered
2022-12-08
Start date
2022-11-30
Completion date
Unknown
Last updated
2023-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others(Health functional food) : -Ingestion method Experimental group (oraCMU): 2 times a day, 1 pack a day. Put it in your mouth after brushing your teeth in the morning or before going to bed in the

Sponsors

Seoul National University Bundang Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients visiting the hospital with peri-implant inflammation • A person who agrees to the study and is able to communicate • Adults over 20 and under 70 with good overall health • Those with mild to moderate inflammation and PPD exceeding 5 mm, bleeding or suppression upon probe, and loss of limbic bone exceeding 2 mm • A person who has agreed to periodontal therapy (gingival curattage) after local anesthesia for the area of inflammation around the implant • If there are multiple areas of inflammation around the implant in one person, select the worst area

Exclusion criteria

Exclusion criteria: • a person with an uncontrolled systemic disease • A person who has taken antibiotics within one month of visit 1 or is likely to take antibiotics during the study period; • Pregnant women or nursing women • People with acute symptoms around the prosthesis • A person who is sensitive to lactobacillus products including dairy products or has allergies (rhinitis, rash, diarrhea, abdominal pain, vomiting, itching, etc.) • A person who has consumed lactobacillus-containing food or health functional food within one week of the first visit;

Design outcomes

Primary

MeasureTime frame
Bleeding on probing (BOP)

Secondary

MeasureTime frame
Gingival index (GI);Periodontal pocket depth (PD);Plaque inex (PI);oral microbiome

Countries

Korea, Republic of

Contacts

Public ContactHyo-Jung Lee

Seoul National University Bundang Hospital

periolee@gmail.com+82-31-1588-3369

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026