None listed
Conditions
Interventions
Drug : Anesthesia was induced with continuous infusion of remimazolam at a rate of 6mg/kg/hr(0.1mg/kg/hr) until the loss of consciousness (LoC) of the patient. Anesthesia was maintained with 1-2mg/kg/
each patient’s response determined the target Ce of remifentanil administered to the next patient. A response was considered successful if HR and MBP values recorded 1 minute after intubation did not
if they did, a failed response was determined. If a response was successful, the target concentration of remifentanil was lowered by 0.5 ng/mL for the next patient
if a response failed, the target concentration of remifentanil was increased by 0.5 ng/mL.
Sponsors
Pusan National University Dental Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients scheduled to undergo oral and maxillofacial surgery American Society of Anesthesiologist Physical Status (ASA PS) 1,2
Exclusion criteria
Exclusion criteria: allergic history (remifentanil or any benzodiazepine drugs)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dose of remifentanil associated 50% probability for adequate depth of anesthesia for nasotracheal intubation | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean arterial pressure, heart rate | — |
Countries
Korea, Republic of
Contacts
Public ContactEun-Ji Choi
Pusan National University Dental Hospital
Outcome results
None listed