Adequate infusion rate of remimazolam for induction of general anesthesia in elderly patients aged 65 or older

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0007902

Enrollment

Registered

2022-11-11

Start date

2022-12-02

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others( Infusion rate) : The infusion rate of remimazolam in the first patient is 0.1 mg/kg/min (The minimum infusion rate that the manufacturer recommends). If the patients lose responsiveness to lig

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Americal Society of Anesthesiologists physical status I - III 2) Aged 65 years and more 3) Elective surgery under general anesthesia

Exclusion criteria

Exclusion criteria: 1) patients who are contraindicated in benzodiazepine (e,g., allergy to drug or have a history of hypersensitivity reactions) 2) drug or alcohol addiction 3) neuromuscular disease or mental illness 4) metabolic disease 5) emergency surgery 6) body mass index >30kg/m2 or <18.5kg/m2 7) patient's refusal 8) patients in shock or coma 9) patients who are contraindicated to remiamazolam such as acute narrow-angle glaucoma, sleep apnea, severe or acute respiratory failure, galactose intolerance, lactase deficiency, glucose-galactose malabsorption, severe hypersensitivity to dextran 40.

Design outcomes

Primary

Measure	Time frame
Loss of responsiveness to light shaking patient's shoulders	—

Secondary

Measure	Time frame
blood pressure;heart rate	—

Countries

Korea, Republic of

Contacts

Public ContactHeejoon Jeong

Samsung Medical Center

hj2415@hanmail.net+82-2-3410-0841

Outcome results