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Clinical outcomes of Xen45 gel stent implantation

Clinical outcomes of Xen45 gel stent implantation with open conjunctival approach and mitomycin C in open-angle glaucoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0007873
Enrollment
20
Registered
2022-11-03
Start date
2021-10-20
Completion date
Unknown
Last updated
2022-11-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Pusan National University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Patients with OAG who underwent ab externo Xen45 gel stent implantation with open conjunctiva approach at the Department of Ophthalmology, Pusan National University Hospital (2) Patients were followed up for at least 12 months postoperatively. (3) If both eyes had Xen45 gel stent implantation, the first eye underwent surgery was included.

Exclusion criteria

Exclusion criteria: (1) Patients who had secondary glaucoma, neovascular glaucoma (except pseudoexfoliation glaucoma, pigmentary glaucoma) (2) previous glaucoma surgery history (except uncomplicated cataract extraction) (3) neurological disease, or retinal disease that could affect the visual field or alter the optic nerve.

Design outcomes

Primary

MeasureTime frame
Kaplan–Meier’s survival analyses were used to evaluate the success rate according to the criterion. The prognostic factors of surgical failure were evaluated using Cox’s proportional hazard regression analysis with enter method.

Secondary

MeasureTime frame
pre- and postoperative intraocular pressure/number of glaucoma medication/best corrected visual acuity, bleb morphology, postoperative complications

Countries

Korea, Republic of

Contacts

Public ContactSangwoo Moon

Pusan National University Hospital

anstkddn0421@hanmail.net+82-51-240-7326

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026