None listed
Conditions
Interventions
None listed
Sponsors
Daejeon Korean Medicine Hospital of Daejeon University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 45 to 84 2. Diagnosed with mild cognitive impairment based on DSM-5 criteria 3. Clinical Dementia Rating of 0.5 4. MoCA-K 22 points or less. 5. Patients who understand the questionnaire himself/herself or with the help of caregivers. 6. Participants who voluntarily signed an informed consent form by himself/herself or a legal representative.
Exclusion criteria
Exclusion criteria: 1. Patients with encephalopathy, brain damage, or mental retardation that can influence cognitive function 2. Histories of brain diseases such as Huntington's disease, normal hydrocephalus, or brain tumors 3. Gastric, endocrine, or cardiovascular diseases that are not controlled by diet or medication 4. Diabetes that is not controlled by hypoglycemic agents or insulin 5. Severe liver disease or severe renal disease that requires dialysis (e.g. over 2 times the upper reference limit of AST, ALT, ?-GTP at screening) 6. Aplastic anemia or malignant disease such as cancer. 7. Seriously unstable medical conditions (the investigator will decide based on vital signs, laboratory test results, etc.) 8. Diagnosed with psychiatric disorders based on DSM-5 criteria (e.g histories of major psychiatric disorders such as schizophrenia, bipolar disorder, delusional disorder, depressive disorders, or alcohol or substance use disorder) 9. Fertile women 10. Not understand an informed consent form or hard to participate in the study due to mental retardation, emotional or intellectual issues 11. Participants with blindness, hearing loss, or severe language disorders have difficulty in examination 12. Not appropriate to participate in this study depending on decision of investigators
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Korean version of Montreal Cognitive Assessment (MoCA-K) | — |
Secondary
| Measure | Time frame |
|---|---|
| Korean version of Alzheimer's disease assessment scale-cognitive subscale (ADAS-K-cog);Perceived Stress Scale (PSS);Beck Depression Inventory (BDI);Insomnia Severity Index (ISI);Simplified Nutritional Appetite Questionnaire (SNAQ);EuroQol-5 Dimension (EQ-5D);Integrative Medicine Patient Satisfaction Scale (IMPSS);Serum cytokine analysis | — |
Countries
Korea, Republic of
Contacts
Public ContactDong Hoon Kang
Daejeon Korean Medicine Hospital of Daejeon University
Outcome results
None listed