The effect of additional use of remimazolam and flumazenil on the recovery of anesthesia in propofol based total intravenous anesthesia for dental treatment in mentally disabled outpatients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0007794

Enrollment

Registered

2022-10-12

Start date

2022-12-05

Completion date

Unknown

Last updated

2023-08-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : In the case of propofol group, anesthesia is induced at 3-5µg/ml using propofol intravenous (1.5~2mg/kg) or target-controlled infusion (TCI) and maintenance is performed using target concentrat

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Adult mentally disabled patients who were expected to undergo dental treatment under general anesthesia at the National Dental Care Center for Persons with Special Needs at Seoul National University Dental Hospital 2. American Society of Anesthesiologists (ASA)physical classification II-III 3. The patient understands the procedure for participating in a clinical trial, and consent can be provided in writing or, if the patient is unable, a legal representative can sign for it

Exclusion criteria

Exclusion criteria: 1. American Society of Anesthesiologists (ASA)physical classification IV-V 2.BMI > 35kg/m^2 3. Allergies to anesthetic or analgesic medications (propofol, remifentanil, remimazolam, rocuronium bromide, sugammadex, flumazenil) 4. Patients who receive the following medications within 24 hours prior to general anesthetics: anxiolytics, antipsychotics, rifampicin, succinycholine, neostigmine, flumazenil, cyclosporin 5. Patients with tracheostomy 6. Previous participant within 6 month 7. anticipated within 1hour surgery

Design outcomes

Primary

Measure	Time frame
length of Difference of anesthetic care unit stay [ Time Frame: immediately after discharge from the post-anesthetic care unit ] length of post-anesthetic care unit stay (minute)	—

Secondary

Measure	Time frame
time of eye opening;time of extubation;Modified Aldrete score within 5 minutes of arrival at the post-anesthetic care unit;postoperative quality of recovery score-15;Incidence of postoperative nausea and vomiting during the first 24 hours postoperatively	—

Countries

Korea, Republic of

Contacts

Public ContactSooyoung Jeon

Seoul National University Dental Hospital

drjeonsy@gmail.com+82-2-2072-3013

Outcome results