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Plasma neutrophil gelatinase-associated lipocalin (NGAL) concentration of living liver transplant recipients according to the albumin administration during surgery: prospective, randomized control trial

Plasma neutrophil gelatinase-associated lipocalin (NGAL) concentration of living liver transplant recipients according to the albumin administration during surgery: prospective, randomized control trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0007760
Enrollment
318
Registered
2022-09-30
Start date
2022-10-10
Completion date
Unknown
Last updated
2026-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : To maintain the mean arterial blood pressure of 70mmHg or more during the surgery, we will adjust the amount of crystalloid and colloid based on the hemodynamic parameters of the Swan-Ganz cath
however, rescue albumin administration was permitted at the attending anesthesiologist's discretion when judged clinically necessary (usual care). Treatment group: 20% albumin is infused at a rate of

Sponsors

Samsung Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Adult recipients (>= 19) Patients with preoperative creatinine level < 2.0 mg/dl

Exclusion criteria

Exclusion criteria: chronic kidney disease preoperative renal replacement therapy liver-kidney transplantation candidate kidney transplant recipients hepatorenal syndrome

Design outcomes

Primary

MeasureTime frame
NGAL level

Secondary

MeasureTime frame
NGAL level;creatinine;albumin level;Postoperative acute kidney injury;Postoperative pulmonary edema assessed by chest roenterogram;Graft failure;Readmission;mortality;peak AST and ALT;Surgical complication assessed with Clavien-Dindo classification;safety outcome related to albumin therapy

Countries

Korea, Republic of

Contacts

Public Contactjeayoun kim

Samsung Medical Center

kimjy0705@naver.com+82-2-3410-6580

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Jul 23, 2026