Comparison of postoperative analgesic effects of two different doses of intrathecal morphine injection in patients receiving laparoscopic donor right hepatectomy; a randomized non-inferiority trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0007751

Enrollment

Registered

2022-09-29

Start date

2022-09-26

Completion date

Unknown

Last updated

2022-10-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Drug name : Morphine Dose : 200mcg or 300mcg single shot before induction of general anesthesia intrathecal injection difference between group : dose of morphine

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who undergo laparoscopic living donor right hepatectomy for liver transplantation ASA physical status I or II

Exclusion criteria

Exclusion criteria: ASA physical status III or more Severe impaired coagulation profile (equal or more than INR 1.5 last coagulation test before the surgery) Patients who have unstable coronary disease or congestive heart failure or arrhythmia or cardiomyopathy Patients who have cerebrovascular disease Pathients who have systemic infection or local infection on lumbar Chronic pain patients Patients who don'r understand about study or refuse the study Patients who have history of severe psychological disease

Design outcomes

Primary

Measure	Time frame
Pain score (Numeric rating scale 0-10)	—

Secondary

Measure	Time frame
Pain score (Numeric rating scale 0-10);Opioid consumption;Nausea, Vomiting, Pruritus;Satisfaction of pain relief;Satisfaction of sleep;First flatus time;Complication (hypoventilation, hypotension, headache);The Korean version of questionnaire of QoR-15 score before and after the surgery;First ambulation;RASS (Richmond Agitation Sedation Scale) score	—

Countries

Korea, Republic of

Contacts

Public ContactSeungwon Lee

Samsung Medical Center

seungwon0209.lee@samsung.com+82-2-3410-0369

Outcome results