None listed
Conditions
Interventions
None listed
Sponsors
Seoul National University Dental Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) subjects with 20 or more natural teeth 2) subjects aged between 19 and 89 and voluntarily participated in this study
Exclusion criteria
Exclusion criteria: 1)subjects having received periodontal therapy within the previous 4 months. 2) Subjects who have taken antibiotics within the previous 3 months. 3) Subjects using immunosuppressants (methotrexate, leflunomide, tacrolimus, cyclosporin, azathioprine) or corticosteroids (oral or injection) within previous 3 months. 4) Subjects with uncontrolled hypertension or diabetes. 5) Subjects with serious cardiovascular disease, respiratory system disease, kidney disease, liver disease, digestive system disease, blood system disease, and/or neuropsychiatric disease complications. 6) Subjects with hyperthyroidism or hypothyroidism. 7) pregnancy. 8) Subjects with autoimmune diseases. 9) Subjects with a history or current malignant tumors in the maxilla or mandible. 10) Subjects who have had or are current drugs abuse or alcohol addiction within previous 1 year. 11) Subjects with ulcerative, bullous, or erosive stomatitis. 12) Subjects with other inflammatory diseases in oral cavity, such as canker sores, herpes simplex and herpes zoster, fungal or bacterial infections except periodontitis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| salivary MMP-8 level | — |
Secondary
| Measure | Time frame |
|---|---|
| Probing pocket depth, gingival recession, clinical attachment level, gingival index, plaque index), tooth loss, bleeding on probing, tooth mobility, furcation involvement, Alveolar bone loss at the mesial and distal | — |
Countries
Korea, Republic of
Contacts
Public ContactHYUNYOUNG SONG
Seoul National University Dental Hospital
Outcome results
None listed