None listed
Conditions
Interventions
Drug : To induce and maintain sedation for MRI scan, propofol monotherapy or propofol and ketamine combination therapy will be administered
(1) Control group
? Sedation-induction drug: propofol 2mg/kg
Sponsors
Samsung Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: ? Pediatric patients undergoing MRI scan under sedation anesthesia ? 3 years to 12 years old ? American Society of Anesthesiologists physical status classification1, 2
Exclusion criteria
Exclusion criteria: Premature infants, History of previous chest surgery, Patients with confirmed upper or lower respiratory tract infections, Patients with airway malformations, Patients with severe lung disease Patients with Body mass index >= 30 Preoperative chest X-ray abnormal findings (eg atelectasis, pneumonia, pneumothorax, pleural effusion, etc.) Patients with increased intracranial pressure or intraocular pressure Patients with uncontrolled hypertension History of convulsions or seizures Patients with hypersensitivity to this drug Patients with hypersensitivity to soybeans or peanuts Patients with cerebrovascular disorders and severe heart failure Patients with insufficiently treated hyperthyroidism Patients with severe cardiac decompensation Pregnant or possibly pregnant women, and lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of atelectasis after sedation | — |
Secondary
| Measure | Time frame |
|---|---|
| airway intervention;Vital sign: Heart rate, Blood pressure, SpO2;complication of sedation: aspiration, hypoxia, poor quality of MRI scan, hypertension, hypotension, bradycardia, tachycardia;any complications after sedation ;postoperative nausea and vomiting;pulmonary complications;parasternal muscle thickness | — |
Countries
Korea, Republic of
Contacts
Public ContactYu Jeong Bang
Samsung Medical Center
Outcome results
None listed