Effect of vitamin C administration on bladder discomfort caused by Foley catheter insertion after surgery in patients undergoing transurethral bladder tumor resection

Effects of intra-operative vitamin C administration on postoperative catheter-related bladder discomfort: A randomized, double-blind, placebo-controlled study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0007684

Enrollment

118

Registered

2022-09-07

Start date

2022-11-03

Completion date

Unknown

Last updated

2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : In vitamin C group, 1 g (4 ml) of vitamin c (ascorbic acid) mixed in 100 ml of a bag of normal saline is administered intravenously just after the induction of anesthesia. Patients in the contr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are 1) scheduled transurethral resection of bladder tumor under general anesthesia 2) aged 20 to 79 years 3) American Society of Anesthesiologists (ASA) Physical Status I or III 4) voluntary participation in this clinical study

Exclusion criteria

Exclusion criteria: 1) Change in surgical plans (e.g. conversion to open surgery) 2) Medical history or condition of overactive bladder, neurogenic bladder, or bladder outflow obstruction 3) Gout 4) Renal or ureter stone 5) Hemochromatosis 6) Daily intake of vitamin C 7) Patient refusal

Design outcomes

Primary

Measure	Time frame
Incidence of CRBD above a moderate grade	—

Secondary

Measure	Time frame
Incidence of CRBD above a moderate grade;Numeric rating scale;Patient satisfaction;Postoperative opioid requirement;Vitamin C-related adverse effects	—

Countries

Korea, Republic of

Contacts

Public ContactJun-Young Park

Asan Medical Center

parkjy@amc.seoul.kr+82-2-3010-3868

Outcome results