Effect and safety for clearance of vancomycin-resistant enterococci in feces through fecal microbiota transplantation

Preliminary studies to expand the indications of fecal microbiota transplantation

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0007585

Enrollment

280

Registered

2022-07-28

Start date

2023-08-01

Completion date

Unknown

Last updated

2023-08-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : 1. Register VRE patients in this study. 2. Stool culture before bowel preparation, bowel preparations are performed to reduce the maximum number of CRE bacteria before transplanta

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: [1] FMT group 1. Men and women over 18 years of age 2. VRE is continuously detected more than 2 times in stool test [2] Control group 1. Men and women over 18 years of age 2. VRE is detected more than 2 times in stool test 3. FMT treatment is rejected but those who agree to participate in this study as a control group

Exclusion criteria

Exclusion criteria: 1. Patients who need urgent treatment such as acute infectious diseases. But include the patients with C. difficile colitis. 2. Patients with the disease-causing severe immunosuppression. 3. Pregnant women 4. Patients to be inappropriate for the study when judged by the researchers

Design outcomes

Primary

Measure	Time frame
VRE negative conversion rate within 90 days	—

Secondary

Measure	Time frame
VRE negative conversion rate within 30 days ;Adverse effect;Changes of microbiome in intestine after FMT	—

Countries

Korea, Republic of

Contacts

Public ContactJung Hwan Lee

Inha University Hospital

endlesmile@naver.com+82-32-890-3557

Outcome results