None listed
Conditions
Interventions
Drug : Each two group will be designated as Desflurane and Sevoflurane. The infusion of volatile anesthetics will be started at the end of main surgical procedure (T1). The change of evoked potential
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Inclusion criteria - American Society of Anesthesiologists physical status I~III - 20 years old = Age < 80 years old - Patients who are scheduled for elective cervical spine operation with intraoperative evoked potentials monitoring - Patients who received written informed consent
Exclusion criteria
Exclusion criteria: Exclusion criteria - Patients with tolerance or hypersensitivity to benzodiazepine - Patients with dependence or addiction to psychotropic drugs or alcohol - Patients with previous brain-related neurosurgery - Patients with inserted status of intracranial device - Pregnant and lactating women - Patients with pacemaker insertion which may interfere evoked potentials test - Patients with acute narrow angle glaucoma - Patients with moderate hypersensitivity to Dextran40 - Patients with history of malignant hyperthermia or having genetic susceptible malignant hyperthermia - Previous hypersensitivity history to halogenated inhalation agents
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The change of amplitude and latency of evoked potentials exam | — |
Secondary
| Measure | Time frame |
|---|---|
| The change of amplitude and latency of evoked potentials exam | — |
Countries
Korea, Republic of
Contacts
Public ContactHeesun Park
Asan Medical Center
Outcome results
None listed