None listed
Conditions
Interventions
None listed
Sponsors
Jeonbuk National University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: * Subject selection criteria ? Adults 18 years of age or older ? Those who have been diagnosed with PPPD among outpatients of neurology and who have performed fMRI examination ? All PPPD diagnostic criteria A to E presented by Barany Society in 2017 must be met. However, diagnostic criterion B is selected when one or more of the exacerbation factors are satisfied. A. At least one of dizziness, unsteadiness, and non-spinning vertigo has been present for more than 3 months. ? One or more symptoms of dizziness lasting more than several hours on 15 or more days in a month. The severity of symptoms may vary. ? Symptoms may not necessarily last all day. B. Symptoms persist without specific triggers, and symptoms are aggravated by the following three factors. If at least one of the three factors is satisfied, it is included in this study. ? Upright posture, ? Active or passive motion that occurs regardless of a specific direction or posture; ? When exposed to moving visual stimuli or complex visual patterns C. PPPD may be preceded by various vestibular syndromes that cause vertigo or postural instability, dizziness, and balance problems. Other neurological or medical conditions or psychological stress may also be antecedents of PPPD. ? If the antecedent is acute or episodic, the characteristic dizziness of PPPD may begin when the antecedent resolves, which may occur intermittently at first and then settle over a continuous course (symptoms are A standards must be met). ? If the antecedent is a chronic syndrome, symptoms may develop slowly at first and then gradually worsen. D. Symptoms result in clinically significant distress and functional decline. E. Symptoms are not better explained by another disease or condition. However, although other diseases may coexist, evidence of other active diseases does not rule out a diagnosis of PPPD. *Criteria for selection of control group - Adults 18 years of age or older - Those who have not been diagnosed with PPPD among outpatient visits to the neurology department and who have performed fMRI - Like the experimental group, the healthy control group should be a person without any psychiatric, neurological, or neuro-otological history. Do not take psychoactive medications and have no history of cerebrovascular disorder.
Exclusion criteria
Exclusion criteria: A. If you have been diagnosed with a psychiatric disorder and are receiving treatment, but have incidental dizziness symptoms, that is, if a psychiatric disorder is judged to be the main problem B. In case of nystagmus and examination findings suggesting acute neurological/neurological disease in neurological/physical examination C. If there is a significant uncontrolled serious medical disease such as cerebrovascular disease, chronic neurodegenerative disease, cognitive impairment, congestive heart failure, or chronic kidney disease that is significant to the previous medical history or underlying disease D. In case of major surgery within 3 months or acute cerebrovascular disease such as stroke E. In-house staff or medical school. dental school. College of Pharmacy. For nursing students F. Those who are unable to cooperate, are pregnant or may become pregnant, and have claustrophobia or panic disorder
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Dizziness Handicap Inventory, Patient Health Questionnaire-9, State-Trait Anxiety Inventory–X1, Big Five Inventory, General Self-Efficacy Scale, Brief Resilience Scale, Fullerton Advanced Balance scale, Activities-specific balance confidence sacle | — |
Secondary
| Measure | Time frame |
|---|---|
| Functional Magnetic Resonance Imaging | — |
Countries
Korea, Republic of
Contacts
Public ContactJin-Ju kang
Jeonbuk National University Hospital
Outcome results
None listed