None listed
Conditions
Interventions
Procedure/Surgery, Others : A person who voluntarily signs a clinical research agreement and satisfies the selection criteria is enrolled in this clinical study. Subjects were randomly assigned to the
Sponsors
Yonsei University Health System, Dental Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Adult patient of 19 years old or older (2) Chronic periodontitis patient who has one or more teeth showing proximal clinical attachment loss of 6 mm or more (3) Patient showing bleeding on probing in more than 25% of the entire dentition (4) Patient showing periodontal bone loss on the radiograph
Exclusion criteria
Exclusion criteria: (1) Patient less than 19 years old (2) Patient having uncontrolled metabolic systemic disease (i.e. uncontrolled diabetes mellitus) (3) Patient having a past medical history of radiotherapy or chemotherapy in the craniofacial area (4) Patient having a past medical history of taking medication which inhibits bone metabolism (i.e. bisphosphonates or denosumab) within the last 4 months (5) Heavy smoker (over 20 cigarette per day) (6) Pregnant or lactating patient (7) Patient having a past dental history of periodontal treatment within the last 6 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| change of probing pocket depth (PPD) | — |
Secondary
| Measure | Time frame |
|---|---|
| bleeding on probing (BoP), gingival index (GI), plaque index (PI);bone fill at the intrabony defect in the radiograph (panoramic and peri-apical x-ray, CBCT);change of the gingival margin and gingival color (intraoral scanner: Virtuo Vivo, Straumann);Patient related outcome measurements (PROMs) in terms of life quality: assessed by visual analog scale (VAS) with OHIP-14 questionnaire | — |
Countries
Korea, Republic of
Contacts
Public ContactJeong Ui-Won
Yonsei University Health System, Dental Hospital
Outcome results
None listed