PlasmaLyte vs Lactated Ringers vs Normal Saline Resuscitation for Acute Pancreatitis

PlasmaLyte vs Lactated Ringers vs Normal Saline Resuscitation for Acute Pancreatitis: A single-center, pragmatic, cluster-randomized trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0007422

Enrollment

Registered

2022-06-20

Start date

2022-10-03

Completion date

Unknown

Last updated

2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Plasma-Lyte 148 group Lactated Ringes group Normal saline group

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: ? In cases who visit the emergency room for symptoms of acute pancreatitis and contact this clinical researcher within 6 hours ? Mild or moderate acute pancreatitis ? Patients who agree to participate in this study and complete the patient consent form

Exclusion criteria

Exclusion criteria: ? Severe acute pancreatitis ? New York Heart Association Class > II heart failure, ? Pulmonary edema, ? Renal failure (Cr > 1.9 mg/dL) ? Abnormal liver function (albumin < 3 mg/dL, or liver cirrhosis diagnosis) ? Clinical signs of hypervolemia: pulmonary congestion, peripheral edema, ascites ? Under the age of 18 ? Pregnancy ? Patient who does not agree to clinical trials

Design outcomes

Primary

Measure	Time frame
Changes in the prevalence of SIRS(Systemic inflammatory response syndrome) after 24 hours.	—

Secondary

Measure	Time frame
CRP after 24 hours, local complications, organ failure, progression to moderate or severe acute pancreatitis, intensive care unit admission, invasive treatment rate, length of hospitalization, mortality, pH and bicarbonate after 24 hours.	—

Countries

Korea, Republic of

Contacts

Public ContactHyung-Keun Kim

The Catholic University of Korea, Uijeongbu St. Mary’s Hospital

hykkim1@gmail.com+82-31-820-3016

Outcome results