Efficacy of acetaminophen-ibuprofen combination at acute postoperative analgesia after laparoscopic gynecology surgery

Efficacy of acetaminophen-ibuprofen combination at acute postoperative analgesia after laparoscopic gynecology surgery: a prospective double-blinded randomized study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0007403

Enrollment

Registered

2022-06-16

Start date

2022-08-17

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : 1) Acetaminophen group: intravenous acetaminophen 1g mixed in 100ml of normal saline 30 minutes before the surgery ends 2) Acetaminophen + ibuprofen group: intravenous acetaminophen 1g and ibup

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients aged between 20-70 undergoing laparoscopic ovarian cystectomy

Exclusion criteria

Exclusion criteria: 1) Refusal to be enrolled in the study 2) Emergency surgery 3) On chronic pain medications 4) Psychiatric disorders 5) Pregnant, lactating women 6) Allergic or hypersensitivity reaction to the medication drugs 7) Renal, hepatic disorders 8) Severe hemolytic anemia 9) Chronic alcoholics 10) History of gastric ulcer or gastrointestinal bleeding 11) Abnormal blood tests, uncontrolled hypertension or other cardiovascular diseases, history of CABG surgery

Design outcomes

Primary

Measure	Time frame
Pain score at recovery room	—

Secondary

Measure	Time frame
Amount of pain medicine used 1;Amount of pain medicine used 2;Amount of pain medicine used 3;Adverse events	—

Countries

Korea, Republic of

Contacts

Public ContactJung Min Koo

The Catholic University of Korea, Seoul St. Mary's Hospital

miniyaa623@gmail.com+82-2-2258-2263

Outcome results