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Comparison of incidence of emergence agitation in adult patients after nasal surgery under general anesthesia: inhalation anesthesia with sevoflurane vs. intravenous anesthesia with remimazolam: a pilot study

Comparison of incidence of emergence agitation in adult patients after nasal surgery under general anesthesia: inhalation anesthesia with sevoflurane vs. intravenous anesthesia with remimazolam: a pilot study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0007387
Enrollment
98
Registered
2022-06-14
Start date
2022-08-29
Completion date
Unknown
Last updated
2024-08-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : In the sevoflurane group, the anesthesia is induced with inhaled sevoflurane, and 50% nitrous oxide in oxygen. Anesthesia is maintained in a Bispectral Index Score (BIS) of 40-60 and the patien

Sponsors

Asan Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients undergoing approximately two hours of general anesthesia for rhinoplasty, endoscopic sinus surgery, septoplasty, turbinoplasty, endoscopic endonasal resection, requiring postop both nasal packing. 2) Patients aged 19 to 65 3) Patients who voluntarily agreed to participate in this clinical trial by written informed consent 4) Patients with an American Society of Anesthesiologists physical status of 1to 3

Exclusion criteria

Exclusion criteria: 1) Patients who were allergic to benzodiazepines or propofol 2) Patients with severe hepatic impairment (Child-Pugh class B and C) or chronic kidney disease 3) Patients who have a history of neurologic disease 4) Patients with a history of psychiatric disease according to DSM-IV classification 5) Patients who were allergic to opioids or nonsteroidal anti-inflammatory drugs

Design outcomes

Primary

MeasureTime frame
The occurrence of emergence agitation

Secondary

MeasureTime frame
The duration of emergence agitation;The time between anesthesia reversal to extubation;Pain intensity in the postanesthesia care unit (PACU);Postoperative nausea, vomiting, shivering;Postoperative respiratory complication;Postoperative cough, laryngeal/bronchial spasm, hypoxia

Countries

Korea, Republic of

Contacts

Public ContactJUNG-PIL YOON

Asan Medical Center

wizdumb@naver.com+82-2-3010-1102

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026