Comparison of the difference in arousal according to the degree of neuromuscular blockade under propofol intravenous anesthesia: deep NMB vs intermediate NMB: a randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0007356

Enrollment

106

Registered

2022-06-03

Start date

2022-06-01

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : The degree of neuromuscular relaxation is divided into two groups according to the degree of maintenance of TOFC during surgery (moderate muscle relaxation vs deep muscle relaxation) After that

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patients aged 19 to 70 years undergoing elective cholecystectomy under general anesthesia

Exclusion criteria

Exclusion criteria: BMI>30kg/m2 or <18.5kg/m2; Patients with severe liver disease, with severe kidney disease Neuromuscular disease or mental illness; Those diagnosed with metabolic disease; drug or alcohol addiction; pregnant women, lactating women, Those who are contraindicated in the use of neuromuscular relaxants (rocuronium) and neuromuscular inversion agents (sugammadex)

Design outcomes

Primary

Measure	Time frame
Differences in the incidence of clinical signs of arousal after sugammadex administration according to the difference in muscle relaxation (deep NMB vs intermediate NMB) during steady state of anesthesia	—

Secondary

Measure	Time frame
Difference in BIS value change between two groups (deep NMB vs intermediate NMB) after sugammadex administration during steady state of anesthesia	—

Countries

Korea, Republic of

Contacts

Public ContactDoyeon Kim

Inha University Hospital

kimdoyeon31@gmail.com+82-32-890-3948

Outcome results