Effect of Bi-flow mode, a new non-invasive ventilation method in respiratory failure patients

Effect of Bi-flow mode in mild to moderate respiratory failure patients

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0007352

Enrollment

Registered

2022-06-03

Start date

2022-03-31

Completion date

Unknown

Last updated

2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : It is a cross-over study in which four modes of Uniflow, Biflow 25%, Biflow 50%, and Biflow 75% are applied in random order to each subject. In the subject, the same high flow rate i

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who are hospitalized for respiratory failure (PaO2/FiO2 ratio <300) in intensive care units who need HFNC treatment due to hypoxic or hypercapnic respiratory failure 1) hypoxic respiratory failure: mild/modulate respiratory failure (100mmHg < PaO2/FiO2 =300mmHg) 2) Hypercapnic respiratory failure: Patients with 45-70mmHg of PaCO2 and pH 7.3 or higher in arterial blood gas analysis (ABGA)

Exclusion criteria

Exclusion criteria: 1)Patients who have difficulty applying nasal cannula due to previous facial surgery, trauma, deformity, airway obstruction, etc. 2) Patients whose level of consciousness is unclear or respiratory failure are expected to require mechanical ventilation.

Design outcomes

Primary

Measure	Time frame
ROX index (SpO2/FiO2 ratio) and percutaneous CO2	—

Secondary

Measure	Time frame
Vital signs (pulse rates, respiratory rates) ;nasal pressure-time product (PTP) calculated using catheter;Modified Borg scale	—

Countries

Korea, Republic of

Contacts

Public ContactWoo Jung Seo

Inje University Ilsan Paik Hospital

maoliang8874@gmail.com+82-31-910-7200

Outcome results