Skip to content

Comparing the efficacy of desensitizing toothpastes on dentin hypersensitivity: a randomized clinical trial

Comparing the efficacy of desensitizing toothpastes on dentin hypersensitivity: a randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0007188
Enrollment
60
Registered
2022-04-14
Start date
2020-08-04
Completion date
Unknown
Last updated
2022-05-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Others(Quasi drugs) : participants with DH were randomized into three groups: Group N (n=17), no active ingredient-containing toothpaste (Pleasia fluoride-free)
Group SC (n=18), a toothpaste containing strontium chloride (SC
Sensodyne Original)
Group TP (n=18), a toothpaste containing tricalcium phosphate (TCP
Vussen S). Participants were instructed to manually brush their teeth for 3 min, 3 times per day for 4 weeks with allocated toothpastes and assessed at three times: baseline, 2 weeks, and 4 weeks. At

Sponsors

Kyung Hee University Dental Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (1) Participants above 19 years old (male or female) (2) ASA I or II (3) Participants who voluntarily signed the consent papers (4) Through clinical examination, when probing with 50 g force or exposed root surface responding to air syringe stimulation, patients with two or more teeth, possibly with cervical abrasion; The tooth must be free of dental caries, defective restorations or fractures of the tooth; The tooth must not undergo any procedures that may cause postoperative hypersensitivity, such as restoration, periodontal surgery, orthodontic treatment, within 3 months.

Exclusion criteria

Exclusion criteria: (1) allergy history to drugs or similar chemicals used in this study (2) subjects with history of treatment for DH in 3 months (3) periodic medication of analgesics or antibiotics for medical reasons (4) pregnancy or lactating women (5) subjects with increased acidity ; Anorexia, reflux esophagitis, etc. (6) excessive drinking of acidic food or beverages; 2 times per day of lemon or tomato taking, 1L/ day of acidic beverage (sports, energy or fruit drinking) (7) who have difficulty reading and understanding instructions provided by clinical trial (8) who are judged unsuitable to participate in clinical trial by investigators

Design outcomes

Primary

MeasureTime frame
Schiff sensitivity score

Secondary

MeasureTime frame
visual analog scale

Countries

Korea, Republic of

Contacts

Public ContactHyun-Jung Kim

Kyung Hee University Dental Hospital

kimhyunjung@khu.ac.kr+82-2-958-9330

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026