cold endoscopic mucosal resection vs. endoscopic mucosal resection

Comparisons of cold endoscopic mucosal resection and endoscopic mucosal resection for 10-15 mm sized colorectal polyps, multi-center randomized controlled trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0007178

Enrollment

140

Registered

2022-04-12

Start date

2022-04-14

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : 1. experimental group : cold EMR on 10-15mm size colorectal polyp 2. active comparator group : conventional EMR on 10-15mm size colorectal polyp In cold EMR, endoscopist submucosa

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients will be included in the study if they fulfill the following criteria: • Age of >19 years able to provide written informed consent • patient with 10-15 mm sized colorectal polyp

Exclusion criteria

Exclusion criteria: Patients will be excluded in the study if they fulfill the following criteria: • Age of <19 years • inable to provide written informed consent • patient with confirmed malignant polyp, suspected malignant polyp, previously incomplete resection polyp, subepithelial lesion, pedunculated polyp • inflammatory bowel disease patients, uninterrupted antithrombotic therapy patients, coagulopathy patients

Design outcomes

Secondary

Measure	Time frame
en bloc resection rate;R0 resection rate;procedure time (measured as the time from the submucosal injection to complete removal of the polyp based on endoscopic assessment);intra-procedural and post-procedural adverse effect(immediate bleeding, delayed bleeding, immediate perforation, delayed perforation, post polypectomy syndrome)	—

Primary

Measure	Time frame
local recurrence rate as determined by endoscopic assessment (no visible recurrent polyps) and histological assessment (scar biopsies) on surveillance colonoscopy	—

Countries

Korea, Republic of

Contacts

Public ContactChang Kyo Oh

The Catholic University of Korea, Seoul St. Mary's Hospital

ckdryekd@gmail.com+82-2-829-5120

Outcome results