None listed
Conditions
Interventions
Procedure/Surgery : DJB group - Patients undergoing duodenojejunal bypass with sleeve gastrectomy
SG group - Patients undergoing sleeve gastrectomy
Sponsors
Seoul National University Bundang Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Age over 18 years BMI equal to or greater than 27.5 kg/m2 T2DM duration = 10 years Using insulin, or HbA1c = 7.0% while taking diabetes medication C-peptide level higher than 1.0 ng/mL Presence of type 2 diabetes fulfilling the following criteria Consent to not become pregnant for at least 1 year after surgery Willingness to provide voluntary informed consent
Exclusion criteria
Exclusion criteria: Presence of uncontrolled severe gastroesophageal reflux (LA classification C or more in esophagogastroduodenoscopy) History of previous metabolic surgery for T2DM History of gastrointestinal surgery, such as gastrectomy or anti-reflux surgery, which may affect the result of metabolic surgery Therapy regimen of more than 3 psychiatric drugs owing to poorly controlled psychiatric disorders Suicidal attempts within the last 12 months Treatment for alcohol and drug abuse within the last 12 months Vulnerability factors (lacking mental capacity, pregnancy or planning of pregnancy, lactation) Unsuitability as per the discretion of the researcher
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete remission rate of type 2 diabetes | — |
Secondary
| Measure | Time frame |
|---|---|
| Complete remission/partial remission/improvement rate of type 2 diabetes;Complete remission/improvement rate of hypertension and hyperlipidemia;Complete remission/partial remission of type 2 diabetes;Changes in body composition;Prevalence of GERD;Changes in quality of life;complication rate;mortality rate;Trace element deficiency rate | — |
Countries
Korea, Republic of
Contacts
Public ContactYoung Suk Park
Seoul National University Bundang Hospital
Outcome results
None listed