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Association of genetic polymorphisms in rachidonate 5-lipoxygenase activating protein (ALOX5AP) in patients undergoing vascular intervention.

Relationship between genetic polymorphisms in 5-Lipoxygenase activating protein and peripheral arterial disease

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0007148
Enrollment
129
Registered
2022-04-06
Start date
2019-10-11
Completion date
Unknown
Last updated
2023-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Pusan National University Yangsan Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male

Inclusion criteria

Inclusion criteria: Medical records of patients who underwent vascular intervention at Pusan National University Yangsan Hospital between May 2018 and August 2019 were investigated. Male patients over 55 years of age with an American Society of Anesthesiologists (ASA) physical status 1-3 were included.

Exclusion criteria

Exclusion criteria: Patients with neurological or psychiatric disorders that could make ABI measurements inaccurate due to poor cooperation were excluded.

Design outcomes

Primary

MeasureTime frame
Prevalence of peripheral artery disease for each single nucleotide polymorphism—

Secondary

MeasureTime frame
Genotype with allele frequencies and heterozygosity of ALOX5AP gene polymorphism;Number of peripheral artery disease affected legs by rs9551963 genotype—

Countries

Korea, Republic of

Contacts

Public ContactWon-Kee Min

Korea University Ansan Hospital

ssendara@daum.net+82-31-718-9264

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026