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DCS versus DES for One-month DAPT in patients with ACS: ONE-PASS Trial

DCS versus DES for One-month DAPT in patients with ACS: ONE-PASS Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0007141
Enrollment
3520
Registered
2022-04-01
Start date
2022-08-10
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Medical Device : Eligible subjects will be randomized with a 1:1 ratio either of DCS group or DES group. For percutaneous coronary intervention, the Polymer-free drug-coated stent (BioFreedom Ultra st

Sponsors

Yonsei University Health System, Severance Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age =19 years 2. All subjects who are acceptable candidates for treatment with a DCS or DES because of ACS 3. Provision of informed consent

Exclusion criteria

Exclusion criteria: 1. Current or potential pregnancy 2. Need of oral anticoagulation therapy 3. Inability to follow the patient over the period of 1 year after enrollment, as assessed by the investigator

Design outcomes

Primary

MeasureTime frame
Patient-oriented composite endpoint (POCE): The composite of all-cause death, MI, or any revascularization

Secondary

MeasureTime frame
Device-oriented composite endpoint (DOCE): The composite of cardiovascular death, MI (not clearly attributable to a non-target vessel), or clinically-driven target-lesion revascularization (TLR);All-cause death;Cardiovascular death;Myocardial infarction;Stroke;Stent thrombosis (definite or probable);Any revascularization;Target-vessel revascularization;Non-target vessel revascularization;Target-lesion revascularization;BARC type 2-5 bleeding;BARC type 3-5 bleeding

Countries

Korea, Republic of

Contacts

Public ContactChul-Min Ahn

Yonsei University Health System, Severance Hospital

drcello@yuhs.ac+82-2-2228-8326

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026