None listed
Conditions
Interventions
Drug : Perform anesthesia according to general spinal anesthesia.For single-blinded trial, do not tell the patient which sedatives to use or not.
After standard monitoring, spinal anesthesia is perfor
Sponsors
Asan Medical Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients aged 20 to 80 years 2) Patients scheduled for regular schedule and receiving spinal anesthesia for lower extremity surgery 3) ASA physical status 1-3 4) Patients who voluntarily consented in writing to participate in this clinical trial
Exclusion criteria
Exclusion criteria: 1) Patients who do not consent to study participation 2) Patients with adverse reactions to bupivacaine, dexmedetomidine, remimazolam, phenylephrine, nicardipine, esmolol, or atropine 3) Patients planned not to be sedated during surgery 4) Patients with uncontrolled medical or psychiatric problems 5) Pregnant or lactating patients 6) Patients whose spinal anesthesia range is greater than T8 7) Patients who are judged unsuitable for participation by medical staff for other reasons
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of hypotensive episodes in two groups (patients using dexmedetomidine or remimazolam) who underwent spinal anesthesia for lower extremity surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| Total dose of vasopressors (ephedrine, phenylephrine) administered ;Total amount of fluid;Frequency of hypertensive episodes per hour;Postoperative complications (cardiovascular, neurological, respiratory, delirium, renal function decline, postoperative nausea, vomiting, etc.);sedation score | — |
Countries
Korea, Republic of
Contacts
Public ContactJong-Hyuk Lee
Asan Medical Center
Outcome results
None listed