Effects of Anesthetic agents (propofol vs. remimazolam) on recovery outcomes in patients undergoing arrhythmia catheter ablation

Effects of Anesthetic agents (propofol vs. remimazolam) on recovery outcomes in patients undergoing arrhythmia catheter ablation: a prospective, randomized, and controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0007132

Enrollment

100

Registered

2022-03-30

Start date

2022-03-31

Completion date

Unknown

Last updated

2023-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : 1) Propofol group: Induction with 5 µg/ml of propofol then maintenance with 3 µg/ml 2) Remimazolam group: Induction with 6 mg/kg/hr of remimazolam then maintenance with 1mg/kg/hr

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) ASA class I-IV adult (19-70 years of age) 2) Undergoing elective cathter ablation procedure for atrial fibrillation/flutter under general anesthesia

Exclusion criteria

Exclusion criteria: 1) History of hypersensitivity to benzodiazepines or propofol 2) Moderate liver disease (Child-Pugh B/C) 3) Diagnosed with metabolic disease 4) Pregnant or breast-feeding 5) Acute glaucoma 6) Galactose intolerance, lactose intolerance, or glucose-galactose absorption disorder 7) Severe hypersensitivity to Dextran 40

Design outcomes

Primary

Measure	Time frame
Factors related to emergence (Time to obey commands)	—

Secondary

Measure	Time frame
Hemodynamic stability;Time variables related to emergence (Times to BIS over 80, LMA removal);Modified Aldrete Scores in PACU;Side effects related to drug use	—

Countries

Korea, Republic of

Contacts

Public ContactYoon Joo Chung

Samsung Medical Center

yjchung87@gmail.com+82-2-3410-2468

Outcome results