None listed
Conditions
Interventions
Behavioral : Patients enrolled in this study will be assigned to a high-intensity interval training group, moderate-intensity continuous training group, or control group. The high-intensity interval t
Sponsors
Inha University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients who were diagnosed with Parkinson's disease based on the UK Parkinson's Disease Society Brain Bank Diagnostic Criteria 2) Patients who were aged between 50 and 80 3) Patients with Hoehn and Yahr stage 1 or 2 4) Patients with the disease duration of less than 5 years 5) Patients who had a score = 1 in the MDS-UPDRS part 1 6) Patients who did less than the recommended aerobic exercise proposed by the American College of Sports Medicine (ACSM) (ex. vigorous exercise done <3 times per week, 20 min per session; or moderate exercise done <5 times per week, 30 min per session) 7) Patients who were on stable dopaminergic pharmacotherapy over more than 3 months
Exclusion criteria
Exclusion criteria: 1) Patients with neurological, orthopedic, or cardiac comorbidities that make them unfit to do aerobic exercise 2) Patients who were unable to complete questionnaires due to cognitive impairment 3) Patients on antipsychotics 4) Patients who have symptoms or signs suggesting atypical or secondary parkinsonism (ex. cerebellar signs, supranuclear gaze palsy, apraxia, prominent autonomic failure, or other cortical signs; multiple strokes with stepwise progression of symptoms) 5) Patients who were unavailable for more than 10% of the study period
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in scores of the Non-Motor Symptoms Scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Change in scores of the Montreal Cognitive Assessment;Change in scores of the Beck Depression Inventory;Change in scores of the Apathy Scale ;Change in scores of the Beck Anxiety Inventory;Change in scores of the Pittsburgh Sleep Quality Index;Change in scores of the Epworth Sleepiness Scale ;Change in scores of the RBD screening questionnaire ;Change in scores of the Scales for Outcomes in Parkinson's Disease - Autonomic ;Change in scores of the Parkinson Fatigue Scale ;Change in scores of the King's Parkinson's Disease Pain Scale ;Change in scores of the Parkinson's Disease Questionnaire-39;Change in scores of the MDS-UPDRS part 3 ;Change in maximal aerobic power (V?o2max) | — |
Countries
Korea, Republic of
Contacts
Public ContactJi-Hee Kang
Inha University Hospital
Outcome results
None listed