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A Multicenter and prospective observational study to evaluate the effectiveness and safety of Rosuzet Tablet in patients with acute ischemic stroke

A Multicenter and prospective observational study to evaluate the effectiveness and safety of Rosuzet Tablet in patients with acute ischemic stroke

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0007080
Enrollment
1500
Registered
2022-03-15
Start date
2022-05-02
Completion date
Unknown
Last updated
2022-04-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Chonnam National University Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) patients with acute ischemic stroke or transient ischemic attack with positive DWI lesions within 72 hours of onset and starting treatment with rosuzet within 3 days after admission; 2) one of following a to d items, a) previous station or ezetimibe treatment, b) previous atherothrombotic diseases, needed to statin or lipid lowering agents, c) dyslipidemia, d) admission LDL-C >70 mg/dl; 3) patients signed informed consent

Exclusion criteria

Exclusion criteria: 1) contraindications of rosuzet, (1) sensitivity to rosuzet (rosuvastatin or ezetimibe), (2) active liver diseases, (3) muscle diseases, (4) cyclosporin treatment, (5) severe chronic kidney disease; 2) pregnant women or breastfeeding; 3) ineligible for the study

Design outcomes

Primary

MeasureTime frame
rates of LDL-C <70mg at 3 months

Secondary

MeasureTime frame
secondary outcomes: 1) rates of LDL-C <55mg at 3 months, 2) 3-months recurrent stroke, 3) in-hospital early neurological deterioration, 4) changes of LDL-C between baseline and 3-months

Countries

Korea, Republic of

Contacts

Public ContactChoi Minji

Chonnam National University Hospital

minji2448@naver.com+82-62-220-5240

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026