None listed
Conditions
Interventions
None listed
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) patients with acute ischemic stroke or transient ischemic attack with positive DWI lesions within 72 hours of onset and starting treatment with rosuzet within 3 days after admission; 2) one of following a to d items, a) previous station or ezetimibe treatment, b) previous atherothrombotic diseases, needed to statin or lipid lowering agents, c) dyslipidemia, d) admission LDL-C >70 mg/dl; 3) patients signed informed consent
Exclusion criteria
Exclusion criteria: 1) contraindications of rosuzet, (1) sensitivity to rosuzet (rosuvastatin or ezetimibe), (2) active liver diseases, (3) muscle diseases, (4) cyclosporin treatment, (5) severe chronic kidney disease; 2) pregnant women or breastfeeding; 3) ineligible for the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rates of LDL-C <70mg at 3 months | — |
Secondary
| Measure | Time frame |
|---|---|
| secondary outcomes: 1) rates of LDL-C <55mg at 3 months, 2) 3-months recurrent stroke, 3) in-hospital early neurological deterioration, 4) changes of LDL-C between baseline and 3-months | — |
Countries
Korea, Republic of
Contacts
Chonnam National University Hospital