The effect of anesthetic agent (remimazolam versus etomidate) on post-induction hypotension in coronary artery bypass surgery

The effect of anesthetic agent (remimazolam versus etomidate) on post-induction hypotension associated with general anesthesia in coronary artery bypass surgery: Non-inferiority randomized controlled study

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0007074

Enrollment

148

Registered

2022-03-11

Start date

2022-04-07

Completion date

Unknown

Last updated

2023-05-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : In this study we compared the incidence of hypotension after induction of anesthesia with different anesthetics, etomidate versus remimazolam in patients undergoing coronary artery bypass surge

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Adults who are American society of anesthesia (ASA) class III~IV 2) Patients undergoing coronary artery bypass grafting

Exclusion criteria

Exclusion criteria: 1) Patients with a history of allergy or hypersensitivity to benzodiazepines or etomidate drugs 2) Patients with severe hepatic impairment, such as, patients with Child-Pugh classifications B and C and patients with chronic renal disease 3) Patients with low ejection fraction ( =40%) 4) Patients with diagnosed adrenocortical insufficiency of taking glucocorticoids within 6 months, if ever used

Design outcomes

Primary

Measure	Time frame
Hypotension incidence	—

Secondary

Measure	Time frame
Degree of blood pressure decrement;Hypertension incidence	—

Countries

Korea, Republic of

Contacts

Public ContactEun Jung Oh

Samsung Medical Center

angy02@naver.com+82-2-3410-2470

Outcome results