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Comparison of recovery profiles of propofol, dexmedetomidine, and remimazolam for monitored anesthetic care

Comparison of recovery profiles of propofol, dexmedetomidine, and remimazolam for monitored anesthetic care in patients undergoing upper limb surgery under brachial plexus block: a randomized controlled trial.

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0006902
Enrollment
120
Registered
2022-01-07
Start date
2023-02-23
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : - propofol: 25-75mcg/kg/min continuous infusion - dexmedetomidine: 1mcg/kg loading for 10 minutes followed by 0.2-1.0mcg/kg/hr continuous infusion - remimazolam: 0.3-1mg/kg/hr continuous infusi

Sponsors

Asan Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: *ASA physical status 1-3 *age: 19-80 years *patients who were scheduled to undergo upper limb surgery under brachial plexus block with monitored anesthetic care

Exclusion criteria

Exclusion criteria: * patients who refused to participate in this study * patients with uncontrolled hypertension, hyperthyroidism, or moderate cardiac disease * patients with severe hepatic/renal disease * patients with chronic use of anti-depressant, anti-convulsant, psychotic drugs * patients who abuses drugs or alcohol * patients with severe obstructive sleep apnea * patients with severe communicatino difficulties due to cognitive impairment * patients with allergy to propofol, dexmedetomidine, or remimazolam * patients who are judged inappropriate by attending anesthesiologists to participate in this study for other reasons

Design outcomes

Primary

MeasureTime frame
Time taken for MOAA/S to return to 5

Secondary

MeasureTime frame
Alderete score;duration of brachial plexus block;time taken for MOAA/S to 3

Countries

Korea, Republic of

Contacts

Public ContactHa-Jung Kim

Asan Medical Center

alexakim06@gmail.com+82-2-3010-0338

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026