Comparison of postoperative delirium incidence and recovery quality in elderly patients undergoing major abdominal surgery under general anesthesia with remimazolam or propofol

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0006877

Enrollment

432

Registered

2021-12-27

Start date

2022-08-25

Completion date

Unknown

Last updated

2025-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Propofol or remimazolam was randomly assigned as an anesthetic used for general anesthesia. Both drugs are used so that the Bispectrum index remains below 60 in doses within the approval range

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologist Physical Status (ASA PS) 1, 2, or 3 2. 65 years of age or older. 3. Patients scheduled to undergo major abdominal surgery (stomach, hepatobiliary, pancreas, colon) 4. Patients who voluntarily agreed to participate in this clinical study.

Exclusion criteria

Exclusion criteria: 1.Patients with a history of hypersensitivity to propofol 2.Patients with a history of hypersensitivity to remimazolam 3. Patients with a history of neurological diseases such as stroke and cerebral infarction. 4. Patients with psychiatric diseases such as depression. 5. Patients judged to be inappropriate by the researcher.

Design outcomes

Primary

Measure	Time frame
incidence of delirium.	—

Secondary

Measure	Time frame
Quality of recovery from general anesthesia;Occurrence of postoperative nausea and vomiting;characteristics of electroencephalogram	—

Countries

Korea, Republic of

Contacts

Public ContactByung-Moon Choi

Asan Medical Center

byungmoonchoi7@hanmail.net+82-2-3010-1704

Outcome results