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The effect of chemotherapy-induced QT prolongation on all-cause mortality in cancer patients-a retrospective observational cohort study

The effect of chemotherapy-induced QT prolongation on all-cause mortality in cancer patients-a retrospective observational cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CRIS
Registry ID
KCT0006836
Enrollment
13032
Registered
2021-12-17
Start date
2022-01-01
Completion date
Unknown
Last updated
2022-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

National Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Over 19 years old. Patients treated with anticancer drugs(39 types) that can extend the QT interval at the National Cancer Center Patients who underwent an electrocardiogram

Exclusion criteria

Exclusion criteria: Under 18 years of age It's hard to evaluate QT due to electrocardiogram QRS duration>120ms complete left or right bundle branch blocks, intraventricular conduction delays ventricular pacing atrial fibrillation/flutter second-degree and complete artial-ventricular blocks severely sinus, atrial and ventricular tachyarrhythmia acute coronary sundrome with dynamic ST-T that interfered accurate QT assessment

Design outcomes

Primary

MeasureTime frame
In cancer patients treated with QT-extended anticancer drugs, all cause deaths are confirmed within two years depending on the presence or absence of severe QT extension.—

Secondary

MeasureTime frame
The effect of extending QT by cancer type and anticancer drug on all causative deaths within 2 years—

Countries

Korea, Republic of

Contacts

Public ContactKim Hak Jin

National Cancer Center

drkhj@ncc.re.kr+82-31-920-1276

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026