Effect of remimazolam versus propofol based general anesthesia on intraoperative hemodynamic stability for major spine surgery

Effect of remimazolam versus propofol based general anesthesia on intraoperative hemodynamic stability in prone position for major spine surgery: a randomized controlled trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0006827

Enrollment

Registered

2021-12-09

Start date

2022-03-30

Completion date

Unknown

Last updated

2026-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : When the patient arrives in the operating room, standard monitoring such as EKG, non-invasive blood pressure, oxygen saturation, and BIS is performed. Initiate anesthesia induction with remimaz

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: * ASA physical status 1-3 * Age: 19-80 years old * Patients scheduled for major spinal surgery in the prone position

Exclusion criteria

Exclusion criteria: * denial of consent * Body mass index: less than 15kg/m2 or more than 35kg/m2 * Those with poorly controlled hypertension, hyperthyroidism, or severe or severe heart disease * Patients with contraindications to remimazolam such as severe liver disease, acute narrow-angle glaucoma, shock or coma, acute alcoholism, etc. * Those who are allergic to propofol or midazolam * Those who are judged inappropriate by medical staff to participate in the trial for other reasons

Design outcomes

Primary

Measure	Time frame
the incidence of hypotension	—

Secondary

Measure	Time frame
Cardiac index;Stroke volume;pleth variability index	—

Countries

Korea, Republic of

Contacts

Public ContactHa Jung Kim

Asan Medical Center

alexakim06@gmail.com+82-2-3010-0338

Outcome results