Skip to content

A comparison of respiratory effects of propofol and remimazolam during procedural sedation: a randomized controlled trial.

A comparison of respiratory effects of propofol and remimazolam during procedural sedation: a randomized controlled trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CRIS
Registry ID
KCT0006797
Enrollment
70
Registered
2021-12-02
Start date
2021-12-17
Completion date
Unknown
Last updated
2022-06-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Propofol-remifentanil is administered by target-controlled infusion during the procedure. Their target effect-site concentrations were adjusted to maintain the sedation level between MOAAS 2-

Sponsors

Samsung Medical Center
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Patients with the ASA PS class I~III 2) Patients scheduled for the insertion of central venous access port devices for the delivery of chemotherapy under monitored anesthetic care(MAC)

Exclusion criteria

Exclusion criteria: 1) Patients with severe cognitive dysfunction 2) Body Mass Index > 35 kg / m 2 or <18.5 kg / m 2 3) Severe liver disease 4) Neuromuscular disease or mental illness kidney disease (GRF <30 or under hemodialysis) 5) Those diagnosed with metabolic diseases 6) Drug addiction or alcohol addiction 7) People who have contraindications to benzodiazepine, sevoflurane, or propofol (Patients who have allergies to drugs or have a history of hypersensitivity reactions) 8) acute narrow-angle glaucoma 9) intolerance to galactose, deficiency of Lapp lactase, glucose-galactose absorption disorder 10) severe hypersensitivity to dextran 40

Design outcomes

Primary

MeasureTime frame
Respiratory depression

Secondary

MeasureTime frame
Interventions due to respiratory depression;time to sedation level of MOAAS 2-3 ;time to alertness from the end of the procedure;atelectasis at PACU ;Patient's satisfaction;The operator's satisfaction;Amnesia during the procedure;apnea hypoapnea index ;Tidal volume, minute ventilation, respiratory rate

Countries

Korea, Republic of

Contacts

Public ContactJeayoun Kim

Samsung Medical Center

kimjy0705@naver.com+82-2-3410-1994

Outcome results

None listed

Source: CRIS (via WHO ICTRP) · Data processed: Feb 4, 2026