None listed
Conditions
Interventions
Drug : Group R continuously intravenously injects remimazolam at an injection rate of 6 mg/kg/h to induce general anesthesia. Group P slowly intravenously administers 1.0 -1.5 mg/kg of propofol for 1
Sponsors
Chosun University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Laparoscopic cholecystectomy. Adults over 65 years of age. I, II, III of American Society of Anesthesiologists (ASA) Physical Status classification Patients who voluntarily agreed to participate in this clinical study.
Exclusion criteria
Exclusion criteria: Emergency surgery. Patients with hemodynamic instability Patients with a history of resistance or hypersensitivity to benzodazepine and other anesthetics. Patients with acute narrow-angle glaucoma Neuromuscular disease. Patients with alcohol or drug dependence Patients with chronic renal failure and severe liver disorder (Child Pugh Classification C) Patients with genetic problems such as galactose intolerance, Lap lactase deficiency, or glucose-galactose malabsorption
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time of loss of consciousness | — |
Secondary
| Measure | Time frame |
|---|---|
| BIS or entropy score;Time to reach an anesthesia depth score of 50 or less after administration of the study drug (seconds);Blood pressure and heart rate;Frequency of awakening during surgery;Presence of cardiovascular abnormalities (%);Time to open your eyes after discontinuing the administration of the study drug (minutes) | — |
Countries
Korea, Republic of
Contacts
Public ContactSang Hun Kim
Chosun University Hospital
Outcome results
None listed