None listed
Conditions
Interventions
Drug : The planned operation is performed under normal general anesthesia.
Both groups use sevoflurane as an inhalation anesthetic during surgery after induction of anesthesia.
intergroup arbitration
Sponsors
Kosin University Gospel Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Patients aged 18-65 years 2) Patients expected to undergo general anesthesia for more than 2 hours during elective surgery 3) Patients corresponding to American Society of Anesthesiologist Status 1-2 ? American Society of Anesthesiologist Status 1: Normal healthy patient ? American Society of Anesthesiology Classification 2: Patients with mild systemic disease (mild systemic disease without functional impairment)
Exclusion criteria
Exclusion criteria: 1) Patients under total intravenous anesthesia 2) Emergency surgery patients 2) body mass index = 30 kg/m2 3) Pregnant and lactating women 4) Patients with lung diseases such as asthma and COPD 5) Patients allergic to drugs (including inhaled anesthetics) a. Patients with a history of hypersensitivity to sevoflurane, desflurane, or other halogenated anesthetics b. Patients with a history of hypersensitivity to remifentanil and other fentanyl analogues c. Patients with a history of hypersensitivity to rocuronium and any of its components or neuromuscular blockers 6) Patients with kidney disease (patients with creatinine clearance less than 60ml/min, patients with renal impairment with a baseline blood creatinine value of 1.5 mg/dL or more) 7) Patients with liver dysfunction 8) Patients with neuromuscular junction disease, including patients with myasthenia gravis and myasthenia gravis 10) Patients who have difficulty in voluntary consent; 11) Patients with a history of psychiatric disorders, including those with difficulty in normal communication 12) Past and family history of malignant hyperthermia 13) Patients with convulsions and patients with acute hepatic porphyria
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time required to reach 80 bispectral index after discontinuation of inhaled anesthetic,;Time to open eyes: the time it takes for the patient to open their eyes after stopping the inhaled anesthetic according to a verbal command | — |
Secondary
| Measure | Time frame |
|---|---|
| Time elapsed between discontinuation of inhalation anesthetic and removal of the endotracheal tube;side effects after general anesthesia, such as dizziness, nausea, and vomiting while entering the postanesthesia case unit | — |
Countries
Korea, Republic of
Contacts
Public ContactJu Deok Kim
Kosin University Gospel Hospital
Outcome results
None listed