Effects and mechanisms of remote ischemic conditioning on symptomatic cerebral hyperperfusion syndrome after superficial temporal artery-middle cerebral artery anastomosis in patients with Moyamoya disease

Effects and mechanisms of remote ischemic conditioning on symptomatic cerebral hyperperfusion syndrome after superficial temporal artery-middle cerebral artery anastomosis in patients with Moyamoya disease: a randomized controlled trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0006733

Enrollment

136

Registered

2021-11-10

Start date

2021-11-02

Completion date

Unknown

Last updated

2021-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Procedure/Surgery : The only difference between the remote ischemic conditioning group and the no emote ischemic conditioning group is whether or not remote ischemic conditioning is performed. In the

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Adult patient undergoing superficial temporal artery-middle cerebral artery anastomosis under general anesthesia for moyamoya disease

Exclusion criteria

Exclusion criteria: Patients who do not agree to participate in the study Patients with preoperative neurological deficits

Design outcomes

Primary

Measure	Time frame
Incidence of symptomatic cerebral hyperperfusion syndrome	—

Secondary

Measure	Time frame
Onset of symptomatic cerebral hyperperfusion syndrome;Duration of symptomatic cerebral hyperperfusion syndrome;Incidence of transient ischemic attack;Incidence of cerebral infarction;Incidence of cerebral hemorrahge;Incidence of seizure;Incidence of surgical infection at surgical site;White blood cell count;Serum concentration of neuron specific enolase;Serum concentration of S100ß;Serum concentration of tumor necrosis factor-a;Serum concentration of C-reactive protein;Length of hospital stay;Length of intensive care unit stay;Glasgow outcome scale	—

Measure

Time frame

Onset of symptomatic cerebral hyperperfusion syndrome;Duration of symptomatic cerebral hyperperfusion syndrome;Incidence of transient ischemic attack;Incidence of cerebral infarction;Incidence of cerebral hemorrahge;Incidence of seizure;Incidence of surgical infection at surgical site;White blood cell count;Serum concentration of neuron specific enolase;Serum concentration of S100ß;Serum concentration of tumor necrosis factor-a;Serum concentration of C-reactive protein;Length of hospital stay;Length of intensive care unit stay;Glasgow outcome scale

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Countries

Korea, Republic of

Contacts

Public ContactHyongmin Oh

Seoul National University Hospital

hyungmin0118@naver.com+82-2-2072-3108

Outcome results