The effect of dexmedetomidine and midazolam for the deveolpment of postoperative delirium in eldery patients undergoing spinal anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

CRIS

Registry ID

KCT0006587

Enrollment

200

Registered

2021-09-16

Start date

2021-10-01

Completion date

Unknown

Last updated

2025-08-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : According to the allocated group, dexmedetomidine or midazolam is intravenously administered until the end of surgery, for sedation during surgery.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: elderly patients of 65 years or more

Exclusion criteria

Exclusion criteria: 1) psychotic disorder (schizophrenia, seizure, Parkinson's disease, dementia) 2) severe bradycardia (<45 bpm), sick sinus syndrome, 2nd or 3rd degree AV block) 3) severe hepatic dysfunction 4) severe renal dysfunction 5) recent history of stroke within 6 months 6) alcohol or other drug abuse 7) difficulty of communication 8) preference to general anesthesia 9) ASA PS 4 or more 10) preoperative K-MMSE score less than 20

Design outcomes

Primary

Measure	Time frame
development of postoperative delirium	—

Secondary

Measure	Time frame
severity of postoperative delirium	—

Countries

Korea, Republic of

Contacts

Public ContactA Ram Doo

Jeonbuk National University Hospital

ruiwin3518@gmail.com+82-63-250-1241

Outcome results