Post-induction hypotension associated with general anesthesia : remimazolam versus propofol

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

CRIS

Registry ID

KCT0006573

Enrollment

180

Registered

2021-09-10

Start date

2021-12-01

Completion date

Unknown

Last updated

2023-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Drug : Standard monitoring (non-invasive blood pressure, oxygen saturation, electrocardiograph, the sensor for bispectral index(BIS)) is applied. After preoxygenation with 100% oxygen using a facial

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients with the ASA PS class III~IV 2) Patients scheduled to elective surgery under general anesthesia

Exclusion criteria

Exclusion criteria: 1) Patients with severe cognitive dysfunction 2) Body Mass Index > 35 kg / m 2 or <18.5 kg / m 2 3) Severe liver disease 4) Neuromuscular disease or mental illness kidney disease (GRF <30 or under hemodialysis) 5) Those diagnosed with metabolic diseases 6) Drug addiction or alcohol addiction 7) Emergency surgery 8) Pregnant women or nursing women 9) People who have contraindications to benzodiazepine, sevoflurane, or propofol (Patients who have allergies to drugs or have a history of hypersensitivity reactions) 10) acute narrow angle glaucoma 11) shock or coma status 12) intolerance to galactose, deficiency of Lapp lactase, glucose-galactose absorption disorder 13) severe hypersensitivity to dextran 40

Design outcomes

Primary

Measure	Time frame
the incidence of post-induction hypotension	—

Secondary

Measure	Time frame
Time to loss of consciousness;The incidence of bradycardia;The incidence of awareness/recall	—

Countries

Korea, Republic of

Contacts

Public Contactjeayoun kim

Samsung Medical Center

kimjy0705@naver.com+82-2-3410-6580

Outcome results